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Description

Starting in 2008, large cardiovascular outcome trials (CVOTs) have been carried out to test the safety and efficacy of new glucose-lowering agents, revealing the cardiovascular protective actions of glucagon-like peptide-1 (GLP-1) receptor agonists (GLP-1RAs)

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The next wave of incretin-based therapies is poised to offer significant advantages over the current generation for treating diabetics and for weight loss in those living with obesity

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The introduction of novel GLP-1 receptor agonists with improved efficacy and safety profiles is likely to attract more patients, further bolstering market growth and providing providers with a broader spectrum of options to treat complex cases

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For EtOH-fed mice, the diet contained 2% v/v EtOH (10.8% total calories) in the first wk and the ethanol content increased weekly by 1% until reaching 5% v/v (27% total calorie)

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